Risk factors

Your risk of developing iritis increases if you:

• Have a specific genetic alteration. People with a specific change in a gene that's essential for healthy immune system function are more likely to develop iritis. This change is labeled HLA-B27.
• Develop a sexually transmitted infection. Certain infections, such as syphilis or HIV/AIDS, are linked with a significant risk of iritis.
• Have a weakened immune system or an autoimmune disorder. This includes conditions such as ankylosing spondylitis and reactive arthritis.
• Smoke tobacco. Studies have shown that smoking contributes to your risk.